WITHDRAWN: A narrative to explain worsening secondary progressive multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Defining secondary progressive multiple sclerosis.
A number of studies have been conducted with the onset of secondary progressive multiple sclerosis as an inclusion criterion or an outcome of interest. However, a standardized objective definition of secondary progressive multiple sclerosis has been lacking. The aim of this work was to evaluate the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis,...
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Background Multiple sclerosis (MS) is one of the chronic autoimmune diseases and a progressive disease of the central nervous system that have unknown causes. Objective This study aims to review the environmental risk factors of MS. Methods In this review study, a search was conducted in databases such as PubMed, Scopus, ScienceDirect, Google Scholar and MagIran on related studies published i...
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The pathological substrate of progressive disability in multiple sclerosis is hypothesized to be axonal loss. Differences in the demographic, pathological and radiological features of patients with primary progressive compared with secondary progressive multiple sclerosis raise the question as to whether they actually represent separate clinical entities. So far, large pathological studies comp...
متن کاملThe natural history of secondary progressive multiple sclerosis.
BACKGROUND The onset of secondary progression is a pivotal event in the course of relapsing-remitting (RR) multiple sclerosis (MS). Patients with secondary progressive MS (SPMS) experience continuous worsening of symptoms independent of the occurrence of relapses. Possible risk factors associated with the onset of SPMS remain under investigated in natural history studies of MS disease course. ...
متن کاملBeta‐interferon exposure and onset of secondary progressive multiple sclerosis
BACKGROUND AND PURPOSE Beta-interferons (IFNβ) are the most widely prescribed drugs for patients with multiple sclerosis (MS). However, whether or not treatment with IFNβ can delay secondary progressive MS (SPMS) onset remains unknown. Our aim was to examine the association between IFNβ exposure and SPMS onset in patients with relapsing-remitting MS (RRMS). METHODS A retrospective cohort stud...
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ژورنال
عنوان ژورنال: Multiple Sclerosis and Related Disorders
سال: 2019
ISSN: 2211-0348
DOI: 10.1016/j.msard.2019.05.023